While

Poor: While the temperature reaches 90 or 95 degrees in the daytime, the nights are often chilly.
Better: Although the temperature reaches 90 or 95 degrees in the daytime, the nights are often chilly.

The paraphrase,
The temperature reaches 90 or 95 degrees in the daytime; at the same time the nights are often chilly,
shows why the use of while is incorrect.

In general, the writer will do well to use while only with strict literalness, in the sense of during the time that.

From: William Strunk, Jr., The Elements of Style, 1918.