While

Its use as a virtual equivalent of although is allowable in sentences where this leads to no ambiguity or absurdity.

While I admire his energy, I wish it were employed in a better cause.
This is entirely correct, as shown by the paraphrase,
I admire his energy; at the same time I wish it were employed in a better cause.

 From: William Strunk, Jr., The Elements of Style, 1918.